Posts by Katja Couball
Honoring Women in Science & Sepsis Care

On this International Day of Women and Girls in Science, we celebrate the incredible women driving progress in sepsis research, advocacy, and care—especially the ones on the Global Sepsis Alliance board. We are honored to have exceptional women leaders amongst our executives who contribute significantly to sepsis research, policy, and education. Their dedication shapes the global fight against sepsis and paves the way for future generations of women in science and healthcare.

We asked some of our board members to share their thoughts on the importance of women in science—here’s what they had to say:

Dr. Alison Fox-Robichaud reflects on the legacy and impact of women in science:

"Women scientists have led the way in critical areas, including Nobel Laureates such as Marie Curie and her daughter Irene, through women like Gerty Cori, Rosalyn Yalow, and Barbara McClintock, to name a few.

As I reflect on my more than 35-year journey studying sepsis, I think about the challenges these and other women have overcome to be recognized as leaders in their field of interest. I have met so many amazing women scientists working in our field, from those improving our understanding of sepsis pathogenesis to those studying epidemiology, leading clinical trials, and tackling policy barriers. Persistence, perseverance, and a focus on the end goal are the qualities that drive us."

Halima Salisu Kabara shares her experience and vision for women in science and healthcare:

"I have been involved in the fight against sepsis and now AMR in Nigeria and Africa in general for decades. As a woman in science and the medical field, I am a researcher and a member of the Federated Platform (Colloquium) and several Working Groups.

I have taken it as my responsibility to create awareness and sensitize healthcare professionals on the importance of Infection Prevention and Control to prevent sepsis and AMR. Antibiotic and antimicrobial resistance cannot be allowed to become the next 'tsunami'!

About 80% of sepsis deaths are preventable. For every hour treatment is delayed, the risk of death increases by as much as 8%. Therefore, educating the public about sepsis is paramount to saving lives—being empowered with the correct information to note the signs and seek care immediately.

Women are the pillars of their families and communities. They serve as the life-givers, mothers, peacemakers, entrepreneurs, and providers of care for children and the elderly. It is crucial that we protect and promote the health of women—with a focus on quality, affordability, and equity—for the well-being and development of both current and future generations.

Therefore, more girls and women—the next generation—must be motivated to enter science and the medical field."

A huge thank you to Louise Thwaites (Vietnam), Daniela Souza (Brazil), Halima Salisu Kabara (Nigeria), Imrana Malik (United States), Ulrika Knutsson (Sweden), Alison Fox-Robichaud (Canada), and Maha Aljuaid (Saudi Arabia) for their invaluable contributions to science and healthcare.

Learn more about our board members on the GSA Board Page

More women in science means advancing sepsis research, better healthcare systems, and healthier communities. Today, we honor the past, present, and future of women driving change in the fight against sepsis.


Katja Couball
Mariam Jashi Calls on WHO Executive Board to Prioritize Sepsis

Dr. Mariam Jashi is urging the World Health Organization (WHO) Executive Board and governments worldwide to prioritize sepsis in Universal Health Coverage (UHC) packages, as well as in preparedness and response plans for future pandemics and other health emergencies.

Dr. Jashi, CEO of the Global Sepsis Alliance (GSA), is currently attending the 156th Session of the WHO Executive Board in Geneva as the Secretary-General of the Medical Women’s International Association (MWIA). She expresses her deepest gratitude to the MWIA leadership for the opportunity to advocate for sepsis within the strategic partnership between the two organizations.

On February 4, Dr. Jashi addressed the WHO Executive Board, expressing concern that despite significant progress, 2 billion people are still driven into poverty each year due to catastrophic health expenditures. She called on national governments to prioritize increased political investments in UHC, with a special focus on providing financial protection to the most vulnerable populations.

Dr. Jashi also urged WHO Member States to integrate sepsis into national UHC packages, aligning with the 2030 Global Agenda for Sepsis, launched by the Global Sepsis Alliance at the German Parliament. She emphasized that the global community will not be able to achieve UHC goals without addressing sepsis – a leading cause of death, responsible for at least 11 million fatalities annually, and accounting for 2.6% of healthcare budgets worldwide.

Dr. Jashi concluded her statement by recalling the words of WHO Director-General, Tedros Adhanom Ghebreyesus, who said, “Nobody should die from Sepsis.”

On February 6, Dr. Jashi delivered a second statement, highlighting the urgency of integrating sepsis into emergency preparedness and response plans, including the ongoing negotiations of the Pandemic Accord.

In this statement, Dr. Jashi began by paying tribute to the dedication and sacrifices of WHO staff and healthcare professionals who responded to 45 health emergencies in 2024 alone.

She also stressed that civilians, healthcare workers, and peacekeeping forces are at heightened risk of infections and sepsis during armed conflicts, disease outbreaks, climate crises, and displacement. Specifically, Dr. Jashi noted that 78% of COVID-19 patients in intensive care units had sepsis, and that every future pandemic will increase the risk of this medical emergency. 

Katja Couball
Register for the 8th Annual Meeting of the ESA, 19 March, at the European Parliament

The European Sepsis Alliance is excited to announce its 8th Annual Meeting, that will take place at the European Parliament on 19 March 2025 from 14:30 to 16:30, under the distinguished patronage of MEP, former Commissioner for Health and Food Safety, and ESA Patron, Vytenis Andriukaitis. This year's meeting promises to be a significant occasion for discussing the urgency to include sepsis policies within the broader EU health policy context.

Following the developments and successes in global sepsis advocacy, the objective of this year's event is to engage European policymakers and stakeholders in understanding the intersection of sepsis with existing health threats and frameworks, such as Antimicrobial Resistance (AMR) and pandemic preparedness strategies, the agenda of the European Health Emergency Response Authority (HERA), health management in conflict zones, to name a few. The meeting will delve into how sepsis preparedness is vital to enhance the overall public health strategy of the EU. A new European Parliament and a newly appointed European Commission provide a unique context to create the synergies needed.

Participants will have the opportunity to share best practices, engage in collaborative discussions, and propose concrete solutions that can be implemented at both national and EU levels. Your insights and experiences are invaluable to developing a cohesive approach to policy integration.

The ESA invites all members and stakeholders to mark the calendar for this important gathering and contribute to shaping the future of sepsis policy in Europe. Your participation is essential in advancing the dialogue on sepsis within the European health policy framework.

Register via the form available on the ESA website and indicate whether you will attend in person at the European Parliament or follow the livestream.

Katja Couball
Sepsis Almost Took Dulce's Life: A Call for Greater Awareness in Mexico

I am Dulce from Mexico. I am 32 years old. I was a very healthy, athletic person who always took care of my health. 

I am a psychologist and writer, and I want to raise awareness about sepsis in Mexico.

I had been having stomach pain and occasional nausea for about 8 months, accompanied by a lot of shaking and coldness in my body and stomach. The doctor said it was gastritis, but the standard gastritis treatments didn't work. I left Mexico for 3 months to visit family, so I didn't treat that discomfort any further. I returned to Mexico because I was going to Turkey, but I still had the symptoms. 

Four days before leaving for Turkey, on February 17, 2024, I had an endoscopy, and my stomach appeared fine. But just hours after the study, I started to feel a lot of chills, vomiting, and shaking. I felt like I was going to die. I was very confused, had a fever of 40° Celsius and a blood pressure of 60/20 and I couldn't breathe. I was sitting on the floor enduring the symptoms because the doctor who did the endoscopy said it was a panic attack, but in reality, I was already in septic shock. I lost my sight and strength at that moment and passed out. 

My dad and sister were with me, they quickly picked me up and took me to the hospital. I was lucky enough to be diagnosed immediately with sepsis because my leukocytes were a thousand times above the normal limit, my oxygen was very low, my blood pressure was terribly low, I suffered terrible dehydration due to the fever and dangerous blood clots roamed around my body. However, the doctors could not discover the cause of the sepsis. They destroyed my veins because of the many tests they did to diagnose bacteria, viruses, and fungi but there were no signs of a source of the infection, and my body was collapsing. My body was filled with clots, my lungs were filling with water, the fever wouldn’t go down despite the medication and my heart developed a mitral valve prolapse. On the third day, I was getting pneumonitis and pulmonary atelectasis.

They treated me with antibiotics and serum. When I got better from sepsis and my tests were better, they sent me home, but I still felt terrible and could not eat. Since the doctors couldn't find a cause, they said that the stomach pains and nausea were a psychosomatic thing.

I went home, but I couldn't eat. Therefore, I was admitted again to the hospital to be fed intravenously. I could not eat anything, I was already malnourished and weighed only 88 pounds, but they did not find a cause nor give me a solution to my problem. When I was no longer anemic, they sent me home again, but I still felt terrible. We had to hire a nurse to give me medication at home and to somewhat control and bear the symptoms. Effectively, I was dying at home. 

My sister found another doctor and I went to him. He admitted me again to the hospital and he finally found the cause of the sepsis, an infection of the pancreas (pancreatitis) caused by the gallbladder, which he removed. With the cause removed, my pancreas slowly recovered.

My life changed completely after this experience. I fight every day to be the person I was before, I was left with physical and psychological after-effects like post-traumatic stress disorder, panic attacks every day, insomnia, waking up in the middle of the night, I have episodes of terror, I developed a terrible fear of any type of diseases, I am still undergoing treatment for my lungs for my obstructive pulmonary disease. I get tired easily, and I get dizzy, among other ailments.

After 4 months I am still visiting doctors and I am waiting for studies to verify that my immune system is functioning well.

I want people to be aware of their health. Here in Mexico, it is very common for people not to take infections seriously. They do not investigate diseases in depth, much less take care of themselves to avoid getting sick. Most people in Mexico have the idea they will heal themselves and thus avoid going to the doctor or taking the correct medicines.

The doctors said that if I had taken a few more minutes to get to the hospital, I would have died.


The article above was written by Dulce Vizcaino and is shared with her explicit consent. The views in the article do not necessarily represent those of the Global Sepsis Alliance. They are not intended or implied to be a substitute for professional medical advice. The whole team here at the Global Sepsis Alliance and World Sepsis Day wishes to thank Dulce for sharing her story and for fighting to raise awareness for sepsis.

Katja Couball
Join SelectScience’s Advancing Healthcare Forum: Global Perspectives on Sepsis Diagnostics and Management

On January 14, 2025, at 17:00 CET, join Dr. Ron Daniels, Vice President of the Global Sepsis Alliance (GSA), Dr. Mariam Jashi, CEO of the GSA, Ephraim Tsalik of Danaher Diagnostics, and Sonia Nicholas as moderator for an exclusive live forum hosted by SelectScience®. This roundtable will cover key issues such as the Global Agenda for Sepsis and the broader challenge of sepsis diagnostics, including early detection, pathogen identification, and the integration of diagnostic tools in clinical practice. It's an essential session for laboratory professionals, clinicians, and point-of-care specialists.

Participants can also receive a certificate of attendance for continuing education.



Katja Couball
White House Hosts Historic First-Ever Sepsis Event

We are thrilled to share the news from our friends at End Sepsis. On December 13, 2024, the White House hosted its first-ever sepsis-focused event, marking a milestone in the fight against this global health threat. This is a victory for sepsis advocates and a significant step toward reducing the 350,000 sepsis-related deaths in the United States every year and addressing the life-changing disabilities that sepsis survivors endure.

This historic event at the White House Office of Science and Technology Policy aimed at convening the public and private sector action on early detection and treatment of sepsis.

The event brought together health leaders, advocates, and sepsis experts, it was prompted by the release of the Agency for Healthcare Research and Quality’s Report to Congress, which provides an in-depth assessment of the sepsis burden in the United States. This report, which END SEPSIS helped advocate for, aims to quantify the toll of sepsis on the healthcare system, economy, and population.

Orlaith Staunton, Founder and Executive Director of END SEPSIS, delivered the opening remarks on behalf of patients and families, emphasizing the need for continued advocacy and action. END SEPSIS, has been instrumental in driving a comprehensive federal response to sepsis.

“This Event is a major victory for the sepsis families who have campaigned to have the White House become more proactive on an issue that kills 350,000 Americans annually. We have intensely lobbied the current and past two administrations to do this; we are gratified that our hard work has finally borne fruit,” said Ciaran Staunton, Co-Founder of END SEPSIS and father of Rory Staunton, who died from undiagnosed, untreated sepsis at age 12.

Among the topics discussed were Rory’s Regulations in New York, the first mandatory sepsis protocol in the United States, which has saved over 16,000 lives since its implementation in 2013. These protocols are named in honor of Rory Staunton, whose untimely death was the catalyst for this groundbreaking initiative.

This event underscores our collective mission to raise awareness, improve early diagnosis, and enhance treatment for sepsis. As we continue to fight together against sepsis, we celebrate this achievement and reaffirm our commitment to reducing the global burden of sepsis.

Join us in our mission to fight sepsis, educate the public, and save lives. Together, we can ensure that sepsis is universally recognized as a medical emergency and that patients receive the timely, life-saving care they need.


About Sepsis

Sepsis is a global health crisis affecting 47 to 50 million people every year and causing at least 11 million deaths worldwide—one death every 2.8 seconds. The mortality rate varies between 15% and more than 50% depending on the country, and many survivors face lifelong consequences. In the United States alone, sepsis kills 350,000 Americans annually, underscoring the need for urgent action.

Katja Couball
Graham Segar's Sepsis Story – Surviving Sepsis and Finding Strength

In the summer of 2024, what began as an ordinary day at work soon became the start of a life-threatening journey I never anticipated. I was in the middle of my shift when I felt a sudden, sharp pop in my right hip—a sensation so intense it stopped me in my tracks. I tried to brush it off, thinking it might just be a pulled muscle, but with each step, the pain intensified, radiating through my leg and leaving me barely able to stand. Eventually, I couldn’t take it anymore and decided to leave work early, hoping some rest would bring relief. Little did I know that my life was about to change in ways I could never have imagined.

By the time I got to my car, the pain was unbearable. I couldn’t even move my leg from the gas pedal to the brake without using my hands to physically lift it. Driving home was a terrifying blur, every moment spent fighting the pain that seemed to grow with each passing second. When I finally made it home, the real struggle began. I reached the stairs to my house, but I couldn’t make it up on my own. I had to crawl, step by agonizing step, dragging myself forward. Halfway up, my mom saw me. The look of shock and fear in her eyes was unmistakable. She met me on the stairs, helping me inside as I collapsed in pain. I couldn’t stand, couldn’t even move without feeling like my entire body was shattering from the inside out.

Over the next several days, the pain only worsened, stealing away my ability to do even the simplest tasks. Sleeping became a nightmare; every time I tried to turn over in bed, the pain would jolt me awake, leaving me trapped in a cycle of sleeplessness and agony. I finally went to the doctor, desperate for answers, but instead of finding relief, I was met with a misdiagnosis. They told me it was just a muscle strain, dismissing the pain that was tearing through my body. They had no idea that, inside me, a deadly infection was spreading through my joints and bloodstream—a silent, invisible threat that would soon take over my entire body.

I tried to believe the doctors and tried to convince myself that it would pass. But the pain only grew worse, leaving me feeling more helpless with each passing day. Finally, after more visits and more pleading for answers, I managed to get an MRI. For the first time, I felt a glimmer of hope that I might get some clarity. But even then, fate seemed determined to work against me—they lost my MRI. Days slipped away, each one allowing the infection more time to spread unchecked. I was left waiting in a limbo of pain and uncertainty, feeling my body weaken, wondering how long I could hold on.

Three weeks after the initial symptoms, the truth finally emerged: I had septic arthritis, a rare and deadly infection. By the time they caught it, the infection had spread all throughout my bloodstream. I was in septic shock, a critical and life-threatening state where the infection was no longer contained to one part of my body; it was everywhere. My entire system was under attack, and the doctors were blunt about the reality of my situation. My chances of survival were terrifyingly slim—a mere 4%. Statistically, I should not have survived, and yet, somehow, I was still holding on. But the road to recovery was far from certain. Some doctors told me I’d be okay in two weeks; others said six months; some warned it could take a year before I was myself again. The uncertainty weighed on me, each prognosis a reminder of how fragile my future had become.

Through all of this, my mom became my rock, caregiver, and anchor. She was already working two jobs to support us, and now, on top of everything, she had to become my full-time nurse. Every day, she’d come home after long hours on her feet, exhaustion etched into her face, and then spend a full hour administering my IV antibiotics. It was no easy task; each dose had to be carefully monitored, the medication flowing directly into my veins through a PICC line, ensuring the infection didn’t regain its deadly hold on me. She took on this responsibility with a dedication that only a mother could muster, giving up her rest and well-being to keep me alive. I could see the toll it was taking on her, but she never let her own exhaustion show, never let her fears take over. She held me together when I felt like I was falling apart, giving me strength in my weakest moments.

I was supposed to be starting my senior year of college, a time I’d looked forward to, filled with excitement for graduation, final memories with friends, and the pride of finishing strong. But instead, I found myself trapped, sidelined, and isolated. During the first month and a half of the semester, I was forced to Zoom into classes, watching from a distance as my friends and classmates moved forward while I stayed behind. I didn’t want to miss out on any schoolwork and didn’t want to lose time, but every day was a struggle. Getting accommodations was difficult, and every assignment was a hurdle as I tried to keep up despite the pain and exhaustion. I was determined not to take a fifth year, not to let this disease rob me of my graduation, but every day was a test of endurance, a battle to hold onto the life I had worked so hard to build.

Despite everything, I had a trip to New York City planned, and I didn’t want to miss it. But my vision of exploring the city turned into a very different reality. At every airport, I had to be wheeled through terminals in a wheelchair, watching as people rushed around me, moving freely in ways I no longer could. Once I arrived, I rented a wheelchair just to get around the city. The places I’d once dreamed of visiting on foot became mere glimpses from the seat of a chair, each street and landmark accessible only if someone could push me forward. It was humbling, it was heartbreaking, and it was a painful reminder of everything I had lost. Each night, I returned to the hotel, only to face the impossible task of sleeping with the constant, unrelenting pain. Every small movement sent sharp, stabbing shocks through my body, jolting me awake again and again. Exhaustion became my constant companion, but even sleep was something my body refused to grant.

Back at home, my healthcare routine became a grueling and exhausting cycle. A home health nurse came every week, to monitor my infection, check my vital signs, and manage my PICC line, my lifeline against the infection that had nearly taken me. Three times a week, a physical therapist came to the house, working with me on exercises that pushed my body to the brink, trying to regain the strength I’d lost. Each session was a test of will, leaving me drained, yet still fighting for any scrap of progress I could hold onto. I had to confront a reality I never thought I’d face—a fight for my future, for my health, and for the life I thought would always be mine.

Through all of this, my mom remained by my side. She was my strength, my constant in a world that had been turned upside down. But I knew how much it hurt her to see me in this state, to watch her child suffer through pain no parent should ever have to witness. She hid her own exhaustion, her own heartbreak, but I could see the toll it was taking on her. She was watching her son fight for his life, caught between hope and despair, facing a reality no one could have prepared for.

Eventually, through the relentless dedication of my doctors, the tireless care of my mom, and my own stubborn determination, I began to recover. But it was far from a quick or easy process. The scars, both physical and emotional, will stay with me forever. I survived, but the journey has left me changed in ways I’m still learning to understand. I came face to face with my own mortality, forced to confront the pain, the helplessness, and the reality of a future I almost lost.

I share my story not to dwell on the suffering, but to honor those who stood by me, who fought for me when I couldn’t fight for myself, and to remind others of the deadly reality of sepsis. It’s a silent killer, one that almost stole my life. I am here today because of the relentless love of my mom, the care of my doctors, and a 4% chance that somehow, against all odds, was enough to keep me alive. I am grateful, humbled, and forever changed, with a new understanding of just how precious life truly is.


The article above was written by Graham Segars and is shared with his explicit consent. The views in the article do not necessarily represent those of the Global Sepsis Alliance. They are not intended or implied to be a substitute for professional medical advice. The whole team here at the Global Sepsis Alliance and World Sepsis Day wishes to thank Graham for sharing his story and for fighting to raise awareness for sepsis.

Katja Couball
GSA Joins the Jeddah Ministerial Conference

Dr. Mariam Jashi – CEO of the Global Sepsis Alliance and Global Board Member of the UNITE Parliamentarians Network for Global Health, joined the 4th Ministerial Conference on AMR and the 2nd Plenary Assembly of the AMR Multi-stakeholder Partnership Platform in Jeddah, Saudi Arabia on November 14-16, 2024.

­­­­The Global Sepsis Alliance and UNITE continue awareness-raising efforts among political and global health leaders on the critical importance to synergize AMR and Sepsis advocacy and policy solutions. In fact, the estimated 4.95 million AMR-related deaths are part (36%) of the 13.66 million Sepsis-related annual deaths, and every high-level political dialogue should continuously reflect this important link.

 
 

Within the framework of the Jeddah Ministerial Conference and the 2nd Plenary Assembly, Dr. Jashi had a possibility to discuss the 2030 Global Agenda for Sepsis and its importance to the AMR challenge, with the following representatives of national governments and parliaments:

  • H.E. Hosams Abu Meri - Minister of Health of Latvia

  • H.E. Dr. Sabin Nsanzimana - Minister of Health of Rwanda

  • Prof. Dr. Edgar Franke - Parliamentary State Secretary, Federal Ministry of Health of Germany

  • Dr. Rosena Allin-Khan - Member of the UK Parliament

  • Hon. Margaret Muhanga Mugisa - Minister of State for Health of Uganda.

During the visit, Dr. Jashi also had a unique opportunity to interact and discuss the importance of the 2030 Global Agenda for Sepsis for AMR with Dr. Tedros Adhanom Ghebreyesus - WHO Director-General, Dr. Hanan Balkhy - WHO Regional Director for Eastern Mediterranean, Dr. Hans Kluge - WHO Regional Director for Europe, Dr. Yukiko Nakatani - WHO Assistant Director-General for AMR and other colleagues from the World Health Organization.

The GSA’s CEO had a bilateral meeting with Dr. Benedetta Allegranzi - Technical Unit Head for the IPC Taskforce and the Global IPC Network of WHO, to review the ongoing collaboration and future partnership priorities of WHO HIS Department and GSA.  

Mariam Jashi discussed the 2030 Sepsis agenda and future priorities for the advancement of the Sepsis and AMR agenda with Dr. David Ripin – Executive Vice President of the Clinton Health Access Initiative (CHAI); Peter Beyer – GARDP Deputy Executive Director;  Dr. Ali Tala Asiri - Director General of the Saudi Patient Safety Centre; Damiano de Felice - Chief of External Affairs, CARB-X; John Alter - AMR Action Fund, Head of External Affairs; Dr. Uzma Syed - Director of the Antimicrobial Stewardship Center of Excellence, Good Samaritan University Hospital and Katherine Urbáez - Executive Director of the Health Diplomacy Alliance. GSA CEO also used the opportunity to briefly discuss the new global Sepsis agenda with leaders and senior policymakers in global health of the Wellcome Trust, the World Bank,  IFPMA, and the BEAM Alliance.

The Global Sepsis Alliance and the Regional Sepsis Alliances for Africa, Asia-Pacific, Europe, Eastern Mediterranean, Latin America, and the Caribbeans will further strengthen advocacy efforts with national governments, UN agencies, and multiple stakeholders from public, private, academic, and civil society sectors on the urgency of action for Sepsis and on the critical need to synergize AMR and Sepsis response. 


 

 

Katja Couball